Calcium HMB Manufacturer in China
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Application
Calcium β-hydroxy-β-methylbutyrate monohydrate (HMB-Ca)
Premium sports nutrition and anti-sarcopenia ingredient with proven muscle protein synthesis enhancement
Basic Properties
| CAS No. | 135236-72-5 |
|---|---|
| EINECS No. | 681-140-5 |
| Synonym Name | Calcium HMB monohydrate, Calcium 3-hydroxy-3-methylbutanoate hydrate |
| Molecular Formula | C10H18CaO6·H2O |
| Molecular Weight | 274.32 |
Product Description
Calcium β-hydroxy-β-methylbutyrate monohydrate (HMB-Ca) is the stabilized monohydrated calcium salt of β-hydroxy-β-methylbutyric acid, a natural metabolite of essential amino acid L-leucine. It is a food-grade nutraceutical raw material with excellent water solubility and stable crystal form. HMB-Ca activates muscle protein synthesis and inhibits muscle protein degradation, widely applied in sports nutrition, anti-sarcopenia senior supplements, special medical foods, functional foods and animal nutrition additives worldwide.
Physicochemical Properties
| Property | Specification |
|---|---|
| Appearance | White crystalline powder, free-flowing, no lump |
| Solubility | Freely soluble in warm water, slightly soluble in methanol/ethanol; insoluble in acetone, ether, oils; aqueous solution clear and transparent |
Product Specifications
| Test Item | Specification |
|---|---|
| Appearance | White crystalline powder |
| Ca Assay, % | 13.6~14.8 |
| HMB Purity, % | ≥84.0 |
| Total content, % | ≥99.0 |
| Loss on drying, % | 5.0~7.5 |
| Heavy Metals, ppm | ≤10 |
| Lead, ppm | ≤3 |
| Arsenic, ppm | ≤1 |
| Mercury, ppm | ≤0.1 |
| Cadmium, ppm | ≤1 |
| Total Plate Count | ≤1000 cfu/g |
| Yeast & Molds | ≤50 cfu/g |
| E.coli | Negative |
| Salmonella | Negative |
| Staphylococcus | Negative |
| Pileup density | 0.3~0.6 g/ml |
Mechanism of Action
- HMB is a natural metabolite of L-leucine in human body (only ~5% of leucine converts to HMB)
- Activates mTOR signaling pathway to accelerate skeletal muscle protein synthesis
- Suppresses ubiquitin-proteasome pathway to reduce muscle protein breakdown
- Stabilizes cell membrane structure, reduce oxidative stress and post-exercise muscle damage
- Alleviates delayed onset muscle soreness (DOMS), relieve physical fatigue
- Prevents sarcopenia by maintaining lean muscle mass in aging population
Main Applications
Sports Nutrition Supplements (Largest Application Field)
- Strength fitness & bodybuilding formulas: Build lean muscle, boost strength, accelerate post-workout recovery, reduce muscle soreness
- Commonly compounded with creatine, BCAA, whey protein
- Standard dosage: 1.5–3.0g/day for adults
- Endurance athlete nutrition: Delay exercise fatigue, sustain muscle endurance
Anti-Aging & Elderly Nutraceuticals (Fast-Growing Segment)
- Relieve age-related sarcopenia, improve lower limb muscle strength, reduce fall risk in seniors
- Used in senior milk powder, solid drinks, multi-nutrient complex tablets
Special Medical Purpose Formula Food (FSMP/Clinical Nutrition)
- For post-operation rehabilitation, long-term bedridden patients and chronic wasting diseases
- Mitigate disuse muscle atrophy
- Core raw material of global clinical nutrition products such as Abbott Juven
Functional Food & Beverages
- Approved as new food raw material by China NHC
- Applicable product categories: sports nutrition food, dairy, chocolate, candy, bakery, ready-to-drink beverages
- Label mandatory warning: Not suitable for infants, pregnant women and lactating women; maximum daily intake ≤6g
Animal Feed & Pet Nutrition (Emerging Market)
- Improve lean meat rate, relieve breeding stress, optimize growth performance of young animals
- Widely registered and applied in Europe & North America
Packaging & Storage
| Packaging |
Standard:
Customized packaging available upon request |
|---|---|
| Storage | Store in cool, dry, shaded, well-ventilated warehouse below 30°C; keep tightly sealed to avoid moisture absorption; separate storage from oxidants, strong acids and strong alkalis |
| Shelf Life | 24 months under unopened standard storage conditions |
Disclaimer:
This data is for reference only. Users should conduct tests to verify suitability for specific applications. For further technical support or customized specifications, please contact the supplier.
ABOUT US
HEG Chemical Co., Ltd.
HEG Chemical Co., Ltd. is a globally recognized manufacturer and supplier of organic chemicals and fine chemicals, headquartered in the Innovation Industry Park, High-tech Zone, Hefei, Anhui, China. With a 20,000-square-meter production base.
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HEG Chemical Co., Ltd.
Phase II, Innovation Industry Park, 2800 High-tech zone Hefei Anhui, China 230000
info@hegchem.com
+86 199 6540 1553